Links to Other Discussion Groups and Meetings:

California Separation Science SocietyNortheastern Regional Chromatography Discussion Group

North Jersey Chromatography Group

Chromatography Forum of the Delaware Valley

ICH inc Q2A and Q2B

FDA Part 11 (electronic records)



The US EPA is holding a workshop entitled “Advancing non-targeted analyses of xenobiotic chemicals in environmental and biological media” at their Research Triangle Park, NC facility on August 18-19, 2015.


Tens-of-thousands of chemicals are registered for use in the United States.  The US Environmental Protection Agency is responsible for ensuring the safety of these chemicals and is authorized to regulate those that pose unreasonable risks to human health and/or the environment.  Quantitative exposure data are available for only a small fraction of registered chemicals, hindering assessments of potential health risks to humans, wildlife, and ecosystems.  New methods are therefore required to efficiently generate measurement data for a growing number of chemicals that remain largely unexamined.  Non-targeted measurement methods, including those based on high-resolution mass spectrometry platforms, offer unique means to screen for xenobiotic chemicals in a variety of environmental and biological media.  This workshop will bring together experts in non-targeted screening to discuss innovative methods and best practices for collecting, analyzing, interpreting, storing, and exchanging measurement data related to xenobiotic chemical exposures.


Participants of this workshop will discuss non-targeted analysis “success stories” and help identify:

* Best practices for using non-targeted measurement methods to identify and characterize xenobiotic chemicals in environmental and biological samples.

* Innovative and practical approaches for the analysis, interpretation, and storage of measurement data obtained via non-targeted methods.

* Challenges that may impede widespread use of non-targeted measurement techniques for exposure science.

* Collaborative opportunities to overcome challenges related to existing methodologies and/or information infrastructures.


To find out more, register to participate in person/remotely, or submit an abstract, please visit the workshop website


Jon R. Sobus, Ph.D., US EPA, (919) 541-2232, 

Mark J. Strynar, Ph.D. US EPA, (919) 541-3706,

Elin M. Ulrich, Ph.D. US EPA, (919) 541-3717,